Yes - there are a number of scenarios where might want to slow down - but the CF Pro software (Firecontrol) does some of that work for you as well. For holes specifically I might run about 50% speed or sometimes even lower. Again, very trial and error depending on material. Once you’ve used it for a bit, you’ll get a feel for what makes sense.
I’ve got a thread I made when I setup my table and some of the mistakes I made here:
Welcome fellow Miller Plasma user Be sure to post some pics as you get going!