When it binds loosen the lead screw nut attachment nuts. See if the lead screw now touches the side of the lead screw nut attachment plate.
If it does you’ll need to adjust the gantry alignment (Daniel did a video on the Langmuir setup series - either 5 or 7 I don’t recall which).
Also, make sure you do the Y-axis lead nut attachment procedure with the lead nut in the right place on the lead screw - I recall it being toward the limit of travel near the motor. It’s easy to miss that (it’s in the videos) and just do it more near the center of the lead screw because you’re doing the X axis there.
If none of that fixes it, flip the lead screw end over end and see if it now binds at the other end - suggesting a bent lead screw. You can see the bend if you roll it on a flat plate and see light between the lands of the screw and the plate (you should see light at the grooves).