In Fusion, the pierce / cut height and pierce delay are set in the post processor window. Keep in mind, Fusion will add .02" to your heights. Not sure why, but setting spring back to 0.00" and reducing your pierce / cut heights by .02" will be close to correct.
As far as configuring different tools for different materials, absolutely! We currently have tool defaults for 20 ga thru 3/8". Create your own tool library in Fusion (say Cut45) and copy / paste the existing tool, then edit. You’ll still have to manually enter pierce delay and cut heights in the post processor window. I would suggest running your RazorCut45 at 45A, as thats the settings for the nozzle. (Lower amperage may improve things, but I’ve yet to set it.) As far as speeds / feeds - We took the Hypertherm 45 chart and reduced it 66%. It provides a good starting place to adjust as needed.
Good luck!