Check the voltage at the power supply in the control box. Should be 36 vdc. Also, check the lead screw couplers for slippage— black magic marker on the coupler and the lead screw. Adjusting power supply voltage.pdf (1.8 MB)
It could be EMI interference, too.
I don’t think it’s the power supply, that will cause the steppers to skip, not ‘slow down’. It’s an odd symptom. But I think OP has a Mach3 board from past posts so it may be the controller board acting up…