Can not jog, axis will not move

New to Fusion 360 and Mach 3. Just got my Crossfire up and running, that being said.
System will run a G code program I have loaded, and will run the Break in. Then with out warning I can no longer jog at all, it will run a G code and cut fine but when it stops it will not jog.
I can shut down and manually jog when run a G code or Break in program but when its stops that’s it. can anyone help. I’m a 71 year old retired welder.
Thanks for any help. Johnny

Might be a bad usb cable. Maybe try another. Reboot everything first.

Thanks I’ll try that tomorrow.